The ARC-BTP has implemented high-throughput DNA and RNA sequencing and genotyping technologies within the platform, with the capacity to genotype thousands of samples, or generates large volumes of data from single samples.

The current technologies available in the platform include:

  • Next generation sequencing and genotyping platforms

  • Liquid handling robotics systems

  • Laser capture micro-dissection microscope​

Next Generation Sequencing
SNP Genotyping
High throughput nucleic acid extraction

BTP Core Staff Members


Dr Minique de Castro
Application Specialist: Next Generation Sequencing

Phone: +27 (0)12 529 9483
External links
: Google Scholar link

Dr de Castro holds a PhD degree in Life Sciences at the University of South Africa. At the Genomics Core Facility, she is responsible for library preparation and sequencing using Next Generation Sequencing technologies.


Alister Ngobeni
Application Specialist: High throughput Technologies

+27 (0)12 529 9483

Mr Ngobeni has an MSc Biochemistry degree from the University of Limpopo. He manages daily operations of liquid handling facility for the provision of services to research programs within the ARC and external clients. As part of the liquid handling facility he is responsible for protocols programming and optimization on the Hamilton liquid handlers.


Nick NR. Mokotoane
Application Specialist: Genotyping and Next Generation Sequencing

Phone: +27 (0)12 529 9482

Mr Mokotoane holds a Bachelors and Honors degree in Molecular Biology and Genetics respectively, from the university of the Free State and has also obtained a research-based M.Sc. degree in Veterinary Science from the University of Pretoria.  Although his main focus within the Genomics Core Facility is genotyping he is also involved in the NGS workflow. 


Jonathan Featherston
Application Specialist: Bioinformatics

Phone: +27 (0)12 529 9483

Jonathan has Master's degree from the University of Johannesburg. He is currently engaged in a part-time PhD at the University of Witwatersrand. As part of the Genomics Core Facility Jonathan is involved in the provision of sequencing services, method implementation and has also been involved in bioinformatics support.


Stephanie Cornelissen
Application Specialist: Genotyping and Next Generation Sequencing

Phone: +27 (0)12 529 9481

Ms Cornelissen is currently busy with PhD in Genetics at Stellenbosch University. She is responsible for the optimization and running of Third generation sequencing technologies at the ARC-BTP Genomics Core Facility. She is also involved in library preparation for Next Generation Sequencing and Genotyping of agricultural species as well as humans. Additionally she is responsible for the optimization and running of the Laser Capture Micro-dissection microscope.


Khulekani Khanyile
Application Specialist: Genotyping

Phone: +27 (0)12 529 9482

Mr Khanyile is an application specialist in genomics at the Genomics Core Facility. His expertises are more focused on genome wide Single Nucleotide Polymorphisms (SNPs) genotyping using high-density SNP panels. He also, develops and implements workflows with focus on quality, efficiency and cost.


Annie Chan
Application Specialist: Bioinformatics

 +27 (0)12 529 9481

Ms Chan has a MSc degree in Microbiology from the University of Pretoria. She is responsible for the quality control of the Next Generation Sequencing data and bioinformatics supports at the Genomics Core Facility.

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